Sensitive and selective monitoring of the DNA damage-induced intracellular p21 protein and unraveling the role of the p21 protein in DNA repair and cell apoptosis by surface plasmon resonance-Reference-Cited by-同舟云学术

Sensitive and selective monitoring of the DNA damage-induced intracellular p21 protein and unraveling the role of the p21 protein in DNA repair and cell apoptosis by surface plasmon resonance

Published:2020 Issue:10 Volume:145 Page:3697-3704
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

He Yuhan¹²³⁴⁵,Wang Zixiao¹²³⁴⁵,Hu Yuqing¹²³⁴⁵,Yi Xinyao¹²³⁴⁵^ORCID,Wu Ling¹²³⁴⁵,Cao Zhong⁶⁷⁸⁴⁹^ORCID,Wang Jianxiu¹²³⁴⁵^ORCID

Affiliation:

1. Hunan Provincial Key Laboratory of Micro & Nano Materials Interface Science

2. College of Chemistry and Chemical Engineering

3. Central South University

4. Changsha

5. P. R. China 410083

6. Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation

7. School of Chemistry and Biological Engineering

8. Changsha University of Science and Technology

9. P. R. China 410114

Abstract

Sensitive and selective monitoring of DNA damage-induced intracellular p21 protein is proposed using surface plasmon resonance. The method serves as a viable means for unraveling the role of p21 protein in DNA repair and cell apoptosis.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for Central Universities of the Central South University

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/AN/C9AN02464F

Reference45 articles.

1. p21: A Two-Faced Genome Guardian

2. p21Waf1/Cip1: its paradoxical effect in the regulation of breast cancer