DBU mediated one-pot synthesis of triazolo triazines <i>via</i> Dimroth type rearrangement-Reference-Cited by-同舟云学术

DBU mediated one-pot synthesis of triazolo triazines via Dimroth type rearrangement

Published:2022 Issue:4 Volume:12 Page:2102-2106
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ganai Ab Majeed¹,Pathan Tabasum Khan¹,Sayyad Nisar¹,Kushwaha Babita¹,Kushwaha Narva Deshwar¹,Tzakos Andreas G.²,Karpoormath Rajshekhar¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Discipline of Pharmaceutical Sciences, College of Health Sciences, University of KwaZulu-Natal (Westville), Durban 4000, South Africa

2. Section of Organic Chemistry and Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, 45110, Greece

Abstract

We demonstrate a simple yet efficient one-pot synthesis of two triazolotriazine isomers via DBU mediated Dimroth type rearrangement with excellent yields.

Funder

South African Agency for Science and Technology Advancement

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D1RA07749J

Reference24 articles.

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4. A structure–activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities

5. A Triazolotriazine‐Based Dual GSK‐3β/CK‐1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition

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