A Triazolotriazine‐Based Dual GSK‐3β/CK‐1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition-Reference-Cited by-同舟云学术

A Triazolotriazine‐Based Dual GSK‐3β/CK‐1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition

Published:2019-01-15 Issue:3 Volume:14 Page:310-314
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Redenti Sara¹,Marcovich Irene¹,De Vita Teresa²,Pérez Concepción³,De Zorzi Rita¹,Demitri Nicola⁴,Perez Daniel I.³,Bottegoni Giovanni⁵,Bisignano Paola⁶,Bissaro Maicol⁷,Moro Stefano⁷,Martinez Ana³,Storici Paola⁴,Spalluto Giampiero¹,Cavalli Andrea²,Federico Stephanie¹^ORCID

Affiliation:

1. Department of Chemical and Pharmaceutical SciencesUniversity of Trieste Via Licio Giorgeri 1 34127 Trieste Italy

2. Drug Discovery & Development (D3)Istituto Italiano di Tecnologia Via Morego 30 16163 Genova Italy

3. Centro de Investigaciones BiologicasCSIC Avenida Ramiro de Maeztu 9 28040 Madrid Spain

4. Elettra Sincrotrone Trieste S.C.p.A. SS 14, km 163.5, AREA Science Park 34149 Trieste Italy

5. School of Pharmacy–Institute of Clinical SciencesCollege of Medical and Dental SciencesSir Robert Aitken Institute for Medical ResearchUniversity of Birmingham Edgbaston B15 2TT UK

6. Cardiovascular Research InstituteUniversity of California San Francisco 555 Mission Bay Boulevard South San Francisco CA 94158 USA

7. Molecular Modeling SectionDepartment of Pharmaceutical and Pharmacological SciencesUniversity of Padova Via Marzolo 5 35131 Padova Italy

Funder

Ministero dell’Istruzione, dell’Università e della Ricerca

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201800778

Reference43 articles.