In vivo active organometallic-containing antimycotic agents-Reference-Cited by-同舟云学术

In vivo active organometallic-containing antimycotic agents

Published:2021 Issue:4 Volume:2 Page:1263-1273
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Rubbiani Riccardo¹²³⁴,Weil Tobias⁵⁶⁷⁸⁹^ORCID,Tocci Noemi⁵⁶⁷⁸⁹^ORCID,Mastrobuoni Luciano¹²³⁴,Jeger Severin¹²³⁴,Moretto Marco¹⁰⁷⁸⁹^ORCID,Ng James¹¹¹²¹³¹⁴¹⁵^ORCID,Lin Yan¹¹¹²¹³¹⁴¹⁵^ORCID,Hess Jeannine¹²³⁴^ORCID,Ferrari Stefano¹⁶²³⁴^ORCID,Kaech Andres¹⁷²³⁴,Young Luke¹¹⁸¹⁹²⁰²¹^ORCID,Spencer John¹¹⁸¹⁹²⁰²¹^ORCID,Moore Anthony L.²²¹⁸¹⁹²³²¹^ORCID,Cariou Kevin¹¹¹²¹³¹⁴¹⁵^ORCID,Renga Giorgia²⁴²⁵²⁶²⁷⁹^ORCID,Pariano Marilena²⁴²⁵²⁶²⁷⁹^ORCID,Romani Luigina²⁴²⁵²⁶²⁷⁹^ORCID,Gasser Gilles¹¹¹²¹³¹⁴¹⁵^ORCID

Affiliation:

1. Department of Chemistry

2. University of Zurich

3. 8057 Zurich

4. Switzerland

5. Department of Food Quality and Nutrition

6. Research and Innovation Centre

7. Fondazione Edmund Mach

8. 38010 San Michele all'Adige

9. Italy

10. Unit of Computational Biology, Research and Innovation Centre

11. Chimie ParisTech

12. PSL University

13. CNRS

14. Institute of Chemistry for Life and Health Sciences

15. Laboratory for Inorganic Chemical Biology

16. Institute of Molecular Cancer Research

17. Center for Microscopy and Image Analysis

18. School of Life Sciences

19. University of Sussex

20. Brighton BN1 9QJ

21. UK

22. Biochemistry & Biomedicine

23. Brighton BN1 9QG

24. University of Perugia

25. Department of Medicine and Surgery

26. Piazzale Lucio Severi – Polo Unico Sant’Andrea delle Fratte

27. 06132 Perugia

Abstract

Fungal infections represent a global problem and there is an urgent need for new drugs. In this work, we prepared four novel organometallic derivatives of the frontline antifungal drug fluconazole with very promising in vivo activity.

Funder

Biotechnology and Biological Sciences Research Council

University of Sussex

Agence Nationale de la Recherche

Universität Zürich

Provincia Autonoma di Trento

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

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