Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry-Reference-Cited by-同舟云学术

Discovery of New Broad-Spectrum Anti-Infectives for Eukaryotic Pathogens Using Bioorganometallic Chemistry

Published:2023-11-27 Issue:23 Volume:66 Page:15867-15882
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lin Yan¹,Jung Hyeim²^ORCID,Bulman Christina A.³,Ng James¹,Vinck Robin¹,O’Beirne Cillian¹,Zhong Shuai¹,Moser Matthew S.³,Tricoche Nancy⁴,Peguero Ricardo⁴,Li Robert W.⁵^ORCID,Urban Joseph F.⁶,Le Pape Patrice⁷,Pagniez Fabrice⁷,Moretto Marco⁸,Weil Tobias⁸,Lustigman Sara⁴,Cariou Kevin¹,Mitreva Makedonka²⁹,Sakanari Judy A.³^ORCID,Gasser Gilles¹^ORCID

Affiliation:

1. Chimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005 Paris, France

2. Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, United States

3. Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California 94158, United States

4. Molecular Parasitology, New York Blood Center, Lindsley F. Kimball Research Institute, New York, New York 10065, United States

5. United States Department of Agricultural Research Service (USDA-ARS), Animal Parasitic Diseases Laboratory, Beltsville, Maryland 20705, United States

6. United States Department of Agriculture, Diet, Genomics and Immunology Laboratory, Beltsville, Maryland 20705, United States

7. Nantes Université, CHU de Nantes, Cibles et Médicaments des Infections et de l’Immunité, IICiMed, UR 1155, F-44000 Nantes, France

8. Fondazione Edmund Mach Via E. Mach 1, Research and Innovation Centre, Via E. Mach 1, 38010 San Michele all’Adige, Italy

9. McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri 63108, United States

Funder

Agence Nationale de la Recherche

National Eye Institute

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

National Institute of Allergy and Infectious Diseases

Provincia Autonoma di Trento

China Scholarship Council

H2020 European Research Council

San Francisco Quantitative Biosciences Institute, University of California,

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01333

Reference59 articles.

1. Innovation in neglected tropical disease drug discovery and development

2. Centers for Disease Control and Prevention. Candida auris. https://www.cdc.gov/fungal/candida-auris/index.html.

3. Tackling the emerging threat of antifungal resistance to human health

4. Drug resistance and tolerance in fungi

5. Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018