Inhibition of MARK4 by serotonin as an attractive therapeutic approach to combat Alzheimer's disease and neuroinflammation

Author:

Shamsi Anas12ORCID,DasGupta Debarati3ORCID,Alhumaydhi Fahad A.4ORCID,Khan Mohd Shahnawaz5ORCID,Alsagaby Suliman A.6,Al Abdulmonem Waleed7,Hassan Md. Imtaiyaz1ORCID,Yadav Dharmendra Kumar8

Affiliation:

1. Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, Jamia Nagar, New Delhi 110025, India

2. Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, United Arab Emirates

3. College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109, USA

4. Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia

5. Department of Biochemistry, College of Sciences, King Saud University, Riyadh 11451, Saudi Arabia

6. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah 11932, Saudi Arabia

7. Department of Pathology, College of Medicine, Qassim University, Buraydah, Saudi Arabia

8. College of Pharmacy, Gachon University of Medicine and Science, Hambakmoeiro, Yeonsu-gu, Incheon, 21924, South Korea

Abstract

Mitogen-activated protein kinases (MAPKs) govern various cellular programs and crucial intermediate pathways in signaling.

Funder

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

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