An un-forgotten classic: the nitro-Mannich reaction between nitrones and silyl nitronates catalysed by B(C6F5)3-Reference-Cited by-同舟云学术

An un-forgotten classic: the nitro-Mannich reaction between nitrones and silyl nitronates catalysed by B(C₆F₅)₃

Published:2024 Issue:7 Volume:15 Page:2648-2654
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Guerzoni Michael G.¹^ORCID,van Ingen Yara¹,Babaahmadi Rasool¹^ORCID,Wirth Thomas²^ORCID,Richards Emma¹²^ORCID,Melen Rebecca L.¹^ORCID

Affiliation:

1. Cardiff Catalysis Institute, School of Chemistry, Cardiff University, Translational Research Hub, Maindy Road, Cathays, Cardiff, CF24 4HQ, Cymru/Wales, UK

2. School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff, CF10 3AT, Cymru/Wales, UK

Abstract

Herein we report the B(C6F5)3-catalysed nitro-Mannich reaction between nitrones and silyl nitronates, affording silyl-protected α-nitro hydroxylamines with yields up to 99% and diastereoselectivities up to 99 : 1.

Funder

Royal Society

Leverhulme Trust

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC05672D

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4. Skeletal Editing: Interconversion of Arenes and Heteroarenes

5. Late-stage diversification of indole skeletons through nitrogen atom insertion

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2. Correction: An un-forgotten classic: the nitro-Mannich reaction between nitrones and silyl nitronates catalysed by B(C₆F₅)₃;Chemical Science;2024