The Necessary Nitrogen Atom: A Versatile High-Impact Design Element for Multiparameter Optimization-Reference-Cited by-同舟云学术

The Necessary Nitrogen Atom: A Versatile High-Impact Design Element for Multiparameter Optimization

Published:2017-02-08 Issue:9 Volume:60 Page:3552-3579
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pennington Lewis D.¹^ORCID,Moustakas Demetri T.¹

Affiliation:

1. Medicinal Chemistry and ‡Modeling and Informatics, Alkermes, Plc, 852 Winter Street, Waltham, Massachusetts 02451-1420, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01807

Reference139 articles.

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2. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

3. The Impact of Chemical Probes in Drug Discovery: A Pharmaceutical Industry Perspective

4. The promise and peril of chemical probes

5. How to improve R&D productivity: the pharmaceutical industry's grand challenge

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