Ptxplatin: a multifunctional Pt(<scp>iv</scp>) antitumor prodrug-Reference-Cited by-同舟云学术

Ptxplatin: a multifunctional Pt(iv) antitumor prodrug

Published:2022 Issue:20 Volume:9 Page:5252-5266
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Zhang Ran¹²^ORCID,Zhang Yueyue¹,Tang Liumei¹,Xu Yixing¹,Li Hao¹²,Jiang Xueping¹,Xin Xiangdong¹,Gui Zhongzheng¹²^ORCID

Affiliation:

1. School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu 212100, People's Republic of China

2. Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang, Jiangsu 212100, People's Republic of China

Abstract

Ptxplatin, comprising paclitaxel and cisplatin, intervened in several cellular processes including the p53 apoptosis pathway, mitochondrial damage and ER stress to kill cancer cells.

Funder

High-end Foreign Experts Recruitment Plan of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QI/D2QI01398C

Reference48 articles.

1. Platinum-based drugs: past, present and future

2. Photoactivatable Platinum-Based Anticancer Drugs: Mode of Photoactivation and Mechanism of Action

3. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

4. The side effects of platinum-based chemotherapy drugs: a review for chemists

5. Fuplatin: An Efficient and Low-Toxic Dual-Prodrug

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