Glycyrrhetinic Acid as a Hepatocyte Targeting Ligand-Functionalized Platinum(IV) Complexes for Hepatocellular Carcinoma Therapy and Overcoming Multidrug Resistance

Author:

Huang Xiaochao12,Li Guimei2,Li Huifang2,Zhong Wentian2,Jiang Guiyang1,Cai Jinyuan1,Xiong Qingping1ORCID,Wu Chuang1,Su Kangning1,Huang Rizhen3,Xu Shiliu2,Liu Zhikun1,Wang Meng12,Wang Hengshan2ORCID

Affiliation:

1. Institute of Green Chemistry and Process Enhancement Technology, National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization, Huaiyin Institute of Technology, Huai’an 223003, China

2. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, China

3. Guangxi Key Laboratory of Drug Discovery and Optimization, Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin 541199, China

Funder

Huaiyin Institute of Technology

China Postdoctoral Science Foundation

National Natural Science Foundation of China

National and Local Joint Engineering Research Center for Mineral Salt Deep Utilization

Program of Guangxi Key Laboratory of Drug Discovery and Optimization

Publisher

American Chemical Society (ACS)

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