Molecular recognition and photoprotection of riboflavin in water by a biomimetic host

Author:

Zhang Hong1,Wang Li-Li12,Pang Xin-Yu1ORCID,Yang Liu-Pan1ORCID,Jiang Wei1ORCID

Affiliation:

1. Shenzhen Grubbs Institute, Guangdong Provincial Key Laboratory of Catalysis and Department of Chemistry, Southern University of Science and Technology, Xueyuan Blvd 1088, Shenzhen, 518055, China

2. Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study&Department of Pharmacy and Pharmacology, University of South China, Hengyang, 421001, China

Abstract

A water-soluble tetralactam macrocycle is synthesized and characterized. This macrocycle is able to strongly bind riboflavin (Ka >107 M−1) in water and provides strong photoprotection of riboflavin upon UV irradiation.

Funder

National Natural Science Foundation of China

Shenzhen Science and Technology Innovation Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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