An ortho C-methylation/O-glycosylation motif on a hydroxy-coumarin scaffold, selectively installed by biocatalysis
Author:
Affiliation:
1. Institute of Biotechnology and Biochemical Engineering
2. Graz University of Technology
3. NAWI Graz
4. 8010 Graz
5. Austria
6. Austrian Centre of Industrial Biotechnology
7. Institute of Organic Chemistry
Abstract
To achieve near quantitative dual modification of the hydroxy-coumarin scaffold, the C-methylation had to occur strictly before the O-glucosylation.
Funder
European Commission
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01513E
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