Regioselective synthesis of enantiopure 1,2- and 1,3-dispirooxindoles along with a DFT study-Reference-Cited by-同舟云学术

Regioselective synthesis of enantiopure 1,2- and 1,3-dispirooxindoles along with a DFT study

Published:2023 Issue:10 Volume:21 Page:2143-2161
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Asmari Bardazard Kamal¹,Shahrestani Naeimeh¹^ORCID,Zamani Amirhosein¹,Eskandari Mehdi¹,Jadidi Khosrow¹^ORCID,Hamzehloueian Mahshid²,Notash Behrouz³^ORCID

Affiliation:

1. Department of Organic Chemistry, Shahid Beheshti University, G.C., Tehran 1983963113, Iran

2. Department of Chemistry, Jouybar Branch, Islamic Azad University, Jouybar, Iran

3. Department of Inorganic Chemistry and Catalysis, Shahid Beheshti University, G.C., Tehran 19839 69411, Iran

Abstract

The regio- and diastereoselective synthesis of rigid framework dispirooxindole [indolizidine, pyrrolizidine, and pyrrolidine] derivatives as enantiopure products in 1,2 and 1,3-dispiro regioisomeric forms is reported.

Funder

Iran National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02311C

Reference67 articles.

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3. Catalytic enantioselective cascade Michael/cyclization reaction of 3-isothiocyanato oxindoles with exocyclic α,β-unsaturated ketones en route to 3,2′-pyrrolidinyl bispirooxindoles

4. A DBU-catalyzed Michael–Pinner–isomerization cascade reaction of 3-hydroxyoxindoles with isatylidene malononitriles: access to highly functionalized bispirooxindoles containing a fully substituted dihydrofuran motif

5. Metal-free diastereoselective construction of bridged ketal spirooxindoles via a Michael addition-inspired sequence

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