A serendipitous one-pot synthesis of the octahydro-2<i>H</i>-pyrazino[1,2-<i>a</i>]pyrazine core-Reference-Cited by-同舟云学术

A serendipitous one-pot synthesis of the octahydro-2H-pyrazino[1,2-a]pyrazine core

Published:2024 Issue:70 Volume:60 Page:9428-9431
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Maestri Claudio¹²^ORCID,Minazzi Paolo³,Grell Toni⁴^ORCID,Colombo Valentina⁴^ORCID,Lattuada Luciano⁵^ORCID,Giovenzana Giovanni B.¹³^ORCID,Travagin Fabio¹^ORCID

Affiliation:

1. Dipartimento di Scienze del Farmaco (DSF), Università del Piemonte Orientale, Largo Donegani 2, I-28100 Novara, Italy

2. PRC Ticinum Lab srl, Via Bovio 6, 28100 Novara, NO, Italy

3. CAGE Chemicals srl, Via Bovio 6, 28100 Novara, NO, Italy

4. Dipartimento di Chimica, Università degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy

5. Bracco Imaging SpA, Via Egidio Folli 50, 20134 Milano, Italy

Abstract

An unprecedented nitro-group displacement-rearrangement provides an efficient one-step synthetic access to the octahydro-2H-pyrazino[1,2-a]pyrazine heterobicyclic system.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC03596H

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