Metal-free, one-pot conversion of proline derivatives into 2-aryl-3-iodo pyrrolidines by a sequential scission–iodination–arylation process-Reference-Cited by-同舟云学术

Metal-free, one-pot conversion of proline derivatives into 2-aryl-3-iodo pyrrolidines by a sequential scission–iodination–arylation process

Published:2014 Issue:47 Volume:12 Page:9547-9556
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Batchu Venkateswara Rao¹²,Romero-Estudillo Iván¹²,Boto Alicia¹²,Miguélez Javier¹²

Affiliation:

1. Instituto de Productos Naturales y Agrobiología del CSIC

2. 38206-La Laguna, Spain

Abstract

A sequential radical decarboxylation–oxidation–iodination–arylation process allows the metal-free, direct conversion of proline derivatives into 2-aryl-3-iodopyrrolidines, which are valuable precursors of a variety of heterocycles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB01372G

Reference102 articles.

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