Synthesis of radioiodinated probes to evaluate the biodistribution of a potent TRPC3 inhibitor-Reference-Cited by-同舟云学术

Synthesis of radioiodinated probes to evaluate the biodistribution of a potent TRPC3 inhibitor

Published:2016 Issue:5 Volume:7 Page:1003-1006
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Hagimori Masayori¹²³,Murakami Takahiro¹²³,Shimizu Kinue⁴⁵⁶³,Nishida Motohiro⁴⁵⁶³⁷,Ohshima Takashi⁴⁵⁶³,Mukai Takahiro¹²³

Affiliation:

1. Kobe Pharmaceutical University

2. Kobe 658-8558

3. Japan

4. Graduate School of Pharmaceutical Sciences

5. Kyushu University

6. Fukuoka 812-8582

7. Okazaki Institute for Integrative Bioscience (National Institute for Physiological Sciences)

Abstract

The transient receptor potential canonical 3 (TRPC3) channel is a member of the TRPC family that contributes to the entry of Ca²⁺through the plasma membrane or modulates the driving force for Ca²⁺entry channels.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00023A

Reference19 articles.

1. The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology

2. Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

3. ERK activation and cell growth require CaM kinases in MCF-7 breast cancer cells

4. Ion homeostasis and apoptosis

5. Calcium Signaling

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