Synthesis of 4-thiouridines with prodrug functionalization for RNA metabolic labeling-Reference-Cited by-同舟云学术

Synthesis of 4-thiouridines with prodrug functionalization for RNA metabolic labeling

Published:2022 Issue:4 Volume:3 Page:447-455
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Moreno Sarah¹,Brunner Melanie²,Delazer Isabel²^ORCID,Rieder Dietmar³^ORCID,Lusser Alexandra²^ORCID,Micura Ronald¹^ORCID

Affiliation:

1. Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

2. Institute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

3. Institute of Bioinformatics, Biocenter, Medical University of Innsbruck, Innrain 82, 6020 Innsbruck, Austria

Abstract

Synthetic access to 4-thiouridine (4sU) derivatives with monophosphate prodrug patterns creates additional possibilities for metabolic labeling of RNA for different applications.

Funder

Österreichische Forschungsförderungsgesellschaft

Austrian Science Fund

Vienna Science and Technology Fund

Universität Innsbruck

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CB/D2CB00001F

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