Synthesis and in vitro phantom NMR and MRI studies of fully organic free radicals, TEEPO-glucose and TEMPO-glucose, potential contrast agents for MRI-Reference-Cited by-同舟云学术

Synthesis and in vitro phantom NMR and MRI studies of fully organic free radicals, TEEPO-glucose and TEMPO-glucose, potential contrast agents for MRI

Published:2015 Issue:20 Volume:5 Page:15507-15510
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Soikkeli M.¹²³⁴,Sievänen K.¹²³⁴,Peltonen J.⁵⁶⁴,Kaasalainen T.⁵⁶⁴,Timonen M.⁵⁶⁴,Heinonen P.¹²³⁴,Rönkkö S.⁷⁸⁹⁴,Lehto V.-P.⁷⁸⁹⁴,Kavakka J. S.¹²³⁴,Heikkinen S.¹²³⁴

Affiliation:

1. Laboratory of Organic Chemistry

2. Department of Chemistry

3. University of Helsinki

4. Finland

5. HUS Helsinki Medical Imaging Center

6. Helsinki

7. Department of Applied Physics

8. University of Eastern Finland

9. FIN-70211 Kuopio

Abstract

Two organic radical contrast agents, TEMPO-Glc and TEEPO-Glc, were synthesized and their stabilities and contrast enhancing properties were tested with in vitro NMR and MRI experiments.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C4RA11455H

Reference24 articles.

1. A Positron-Emission Transaxial Tomograph for Nuclear Imaging (PETT)

2. Molecular Imaging and Contrast Agent Database (MICAD) Internet, Bethesda (MD), National Center for Biotechnology Information (US), 2004–2013, http://www.ncbi.nlm.nih.gov/books/NBK5330/

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