The role of biocatalysis in the asymmetric synthesis of alkaloids – an update

Author:

Cigan Emmanuel1ORCID,Eggbauer Bettina1ORCID,Schrittwieser Joerg H.1ORCID,Kroutil Wolfgang1ORCID

Affiliation:

1. Institute of Chemistry, University of Graz, NAWI Graz, BioTechMed Graz, BioHealth, Heinrichstrasse 28/II, 8010, Graz, Austria

Abstract

This review article discusses developments in the chemo-enzymatic synthesis of alkaloids since 2013, showcasing how modern methods of organic synthesis and biocatalysis are combined to establish novel routes towards these important natural products.

Funder

Austrian Science Fund

Karl-Franzens-Universität Graz

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference309 articles.

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3. T.Aniszewski , Alkaloids: Chemistry, Biology, Ecology, and Applications , Elsevier , Boston , 2nd edn, 2015

4. Dictionary of Alkaloids with CD-ROM , ed. J. Buckingham , K. H. Baggaley , A. D. Roberts and L. F. Szábo , CRC Press , Boca Raton, FL , 2nd edn, 2010

5. M.Mahajan , V.Kumar and S. K.Yadav , in Alkaloids: Properties, Applications, and Pharmacological Effects , ed. N. M. Cassiano , Nova Science Publishers , Hauppauge, NY , 2010 , pp. 1–36

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