The effect of light irradiation on a nitro-ruthenium porphyrin complex in the induced death of lung cancer cells in two- and three-dimensional cultures: Insights into the effect of nitric oxide

Author:

Becceneri Amanda Blanque1,Martin Matheus Torelli1,Graminha Angelica Ellen12ORCID,Cominetti Márcia Regina3ORCID,Ford Peter C.4ORCID,Santana da Silva Roberto14ORCID

Affiliation:

1. Laboratory of Photochemistry and Bioinorganic Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Av. do Café, Vila Monte Alegre, Ribeirão Preto, São Paulo, 14040-903, Brazil

2. Institute of Chemistry, São Paulo State University, Av. Prof. Francisco Degni, 55, 14800-900, Araraquara, São Paulo, Brazil

3. Department of Gerontology, Federal University of São Carlos, Rod. Washington Luís, Km 235, São Carlos, São Paulo, 13565-905, Brazil

4. Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93110-9510, USA

Abstract

The effects of the nitro-ruthenium porphyrin complex, RuNO2TPyP, in lung cells using 2D and 3D cell culture models.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

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