(−)-Epicatechin and colonic metabolite 2,3-dihydroxybenzoic acid, alone or in combination with metformin, protect cardiomyocytes from high glucose/high palmitic acid-induced damage by regulating redox status, apoptosis and autophagy-Reference-Cited by-同舟云学术

(−)-Epicatechin and colonic metabolite 2,3-dihydroxybenzoic acid, alone or in combination with metformin, protect cardiomyocytes from high glucose/high palmitic acid-induced damage by regulating redox status, apoptosis and autophagy

Published:2024 Issue:5 Volume:15 Page:2536-2549
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

García-Díez Esther¹^ORCID,Pérez-Jiménez Jara¹²^ORCID,Martín María Ángeles¹²^ORCID,Ramos Sonia¹²^ORCID

Affiliation:

1. Department of Metabolism and Nutrition, Institute of Food Science and Technology and Nutrition (ICTAN), Consejo Superior de Investigaciones Científicas (CSIC), José Antonio Novais 10, Ciudad Universitaria, 28040, Madrid, Spain

2. Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), ISCIII, Spain

Abstract

EC and DHBA, alone or in combination with MET, alleviated glucolipotoxic-induced cardiac damage in cultured cells by regulating the redox status, autophagy and apoptosis.

Funder

Ministerio de Ciencia e Innovación

European Regional Development Fund

Comunidad de Madrid

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO04039A

Reference56 articles.

1. Impact of cocoa flavanols on human health

2. Insight into the potential application of polyphenol-rich dietary intervention in degenerative disease management

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acute Hyperglycemia-Induced Injury in Myocardial Infarction;International Journal of Molecular Sciences;2024-08-04