Two novel ACE inhibitory peptides isolated from longan seeds: purification, inhibitory kinetics and mechanisms

Author:

Nuchprapha Atthasith12345,Paisansak Supawee12345,Sangtanoo Papassara67345,Srimongkol Piroonporn67345,Saisavoey Tanatorn67345,Reamtong Onrapak8910115,Choowongkomon Kiattawee12213145,Karnchanatat Aphichart67345ORCID

Affiliation:

1. Program in Biotechnology

2. Faculty of Science

3. Chulalongkorn University

4. Bangkok 10330

5. Thailand

6. Research Unit in Bioconversion/Bioseparation for Value-Added Chemical Production

7. Institute of Biotechnology and Genetic Engineering

8. Department of Molecular Tropical Medicine and Genetics

9. Faculty of Tropical Medicine

10. Mahidol University

11. Bangkok 10400

12. Department of Biochemistry

13. Kasetsart University

14. Bangkok 10903

Abstract

The isolation and subsequent identification of the two novel ACE-inhibitory peptides, ETSGMKPTEL, and ISSMGILVCL from the longan seeds were achieved. The inhibition mechanism was investigated by molecular docking.

Funder

Chulalongkorn University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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