Hydroxyl radical is a significant player in oxidative DNA damage in vivo-Reference-Cited by-同舟云学术

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Hydroxyl radical is a significant player in oxidative DNA damage in vivo

Published:2021 Issue:15 Volume:50 Page:8355-8360
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Halliwell Barry¹²³⁴^ORCID,Adhikary Amitava⁵⁶⁷⁸^ORCID,Dingfelder Michael⁹¹⁰¹¹⁸^ORCID,Dizdaroglu Miral¹²¹³¹⁴⁸^ORCID

Affiliation:

1. Department of Biochemistry

2. National University of Singapore

3. Centre for Life Sciences

4. Singapore

5. Department of Chemistry

6. Oakland University

7. Rochester

8. USA

9. Department of Physics

10. East Carolina University

11. Greenville

12. Biomolecular Measurement Division

13. National Institute of Standards and Technology

14. Gaithersburg

Abstract

Schematic representation of the important chemical reactions involved in reactive oxygen species-mediated DNA damage.

Funder

National University of Singapore

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CS/D1CS00044F

Reference73 articles.

1. B. Halliwell and J. M. C.Gutteridge , Free Radicals in Biology and Medicine , Clarendon Press , Oxford, UK , 5th edn, 2015

2. Why is the hydroxyl radical the only radical that commonly adds to DNA? Hypothesis: It has a rare combination of high electrophilicity, high thermochemical reactivity, and a mode of production that can occur near DNA

3. Reflections of an aging free radical

4. Oxidative Stress in Cancer

5. Oxidative stress and cancer: have we moved forward?

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