Visible light driven deuteration of formyl C–H and hydridic C(sp3)–H bonds in feedstock chemicals and pharmaceutical molecules-Reference-Cited by-同舟云学术

Visible light driven deuteration of formyl C–H and hydridic C(sp3)–H bonds in feedstock chemicals and pharmaceutical molecules

Published:2020 Issue:33 Volume:11 Page:8912-8918
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kuang Yulong¹²³^ORCID,Cao Hui¹²³,Tang Haidi¹²³,Chew Junhong¹²³,Chen Wei¹²³,Shi Xiangcheng¹²³,Wu Jie¹²³^ORCID

Affiliation:

1. Department of Chemistry

2. National University of Singapore

3. Republic of Singapore

Abstract

A selective hydrogen deuterium exchange reaction with formyl C–H bonds and a wide range of hydridic C(sp³)–H bonds has been achieved by merging tetra-n-butylammonium decatungstate photocatalyst and a thiol catalyst under 390 nm light irradiation.

Funder

Ministry of Education - Singapore

National University of Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC02661A

Reference50 articles.

1. Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

2. Kinetic Isotope Effects in the Study of Organometallic Reaction Mechanisms