Simultaneous quantification of coenzyme A and its salvage pathway intermediates in in vitro and whole cell-sourced samples
Author:
Affiliation:
1. Department of Biochemistry
2. Stellenbosch University
3. Stellenbosch
4. South Africa
Abstract
A method for the quantitative analysis of CoA and its thiolated precursors was developed, addressing the analytical shortcomings of previous methods. Its utility was showcased by analysis ofin vitroenzyme reactions and samples extracted from various bacterial strains.
Funder
National Research Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA00192D
Reference29 articles.
1. E. Strauss , in Comprehensive Natural Products II Chemistry and Biology, ed. L. Mander and H.-W. Liu, Elsevier, Oxford, 2010, pp. 351–410
2. Coenzyme A, more than ‘just’ a metabolic cofactor
3. Recent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development
4. Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides
5. Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Harnessing the Vnn1 pantetheinase pathway boosts short chain fatty acids production and mucosal protection in colitis;Gut;2022-09-29
2. Thiophosphate Analogs of Coenzyme A and Its Precursors—Synthesis, Stability, and Biomimetic Potential;Biomolecules;2022-08-01
3. Staphylococcus aureus Small RNAs Possess Dephospho-CoA 5′-Caps, but No CoAlation Marks;Non-Coding RNA;2022-06-28
4. Vnn1 pantetheinase limits the Warburg effect and sarcoma growth by rescuing mitochondrial activity;Life Science Alliance;2018-07-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3