Installing the “magic methyl” – C–H methylation in synthesis-Reference-Cited by-同舟云学术

Installing the “magic methyl” – C–H methylation in synthesis

Published:2021 Issue:9 Volume:50 Page:5517-5563
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Aynetdinova Daniya¹²³⁴⁵^ORCID,Callens Mia C.¹²³⁴⁵^ORCID,Hicks Harry B.¹²³⁴⁵^ORCID,Poh Charmaine Y. X.¹²³⁴⁵^ORCID,Shennan Benjamin D. A.¹²³⁴⁵^ORCID,Boyd Alistair M.¹²³⁴⁵^ORCID,Lim Zhong Hui¹²³⁴⁵^ORCID,Leitch Jamie A.¹²³⁴⁵^ORCID,Dixon Darren J.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. University of Oxford

3. Chemistry Research Laboratory

4. Oxford

5. UK

Abstract

Following notable cases of remarkable potency increases in methylated analogues of lead compounds, this review documents the state-of-the-art in C–H methylation technology.

Funder

Engineering and Physical Sciences Research Council

Agency for Science, Technology and Research

Leverhulme Trust

GlaxoSmithKline

Clarendon Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CS/D0CS00973C