Computational insights into inhibitory mechanism of azole compounds against human aromatase
Author:
Affiliation:
1. Shanghai Key Laboratory of New Drug Design
2. School of Pharmacy
3. East China University of Science and Technology
4. Shanghai 200237
5. China
Abstract
We investigated the inhibitory mechanism of azole aromatase inhibitors. The results showed that letrozole and imazalil prefer different unbinding pathways.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA19602G
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