A direct entry to polycyclic quinoxaline derivatives <i>via</i> I<sub>2</sub>-DMSO mediated oxidative decarboxylation of α-amino acids and the subsequent Pictet–Spengler cyclization reaction-Reference-Cited by-同舟云学术

A direct entry to polycyclic quinoxaline derivatives via I₂-DMSO mediated oxidative decarboxylation of α-amino acids and the subsequent Pictet–Spengler cyclization reaction

Published:2022 Issue:22 Volume:20 Page:4650-4658
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Samanta Surya Kanta¹,Sarkar Rumpa¹,Sengupta Utsav¹^ORCID,Das Sayan²,Ganguly Debabani²,Hasija Avantika³^ORCID,Chopra Deepak³^ORCID,Bera Mrinal K.¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Engineering Science and Technology (IIEST), Shibpur, Howrah 711 103, WB, India

2. Centre for Health Science and Technology, JIS Institute of Advanced Studies and Research, JIS University, Kolkata, India

3. Crystallography and Crystal Chemistry Laboratory, Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal 462066, India

Abstract

A facile and highly efficient iodine-promoted strategy has been delineated for the synthesis of indolo and pyrrolo[1,2-a]quinoxaline derivatives via an oxidative Pictet–Spengler type amino cyclo-annulation reaction using ∝-amino acids as aldehyde surrogates.

Funder

Science and Engineering Research Board

Council of Scientific and Industrial Research, India

Indian Institute of Science Education and Research Bhopal

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00503D

Reference64 articles.

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