LNA units present in the (2′-OMe)-RNA strand stabilize parallel duplexes (2′-OMe)-RNA/[All-RP-PS]-DNA and parallel triplexes (2′-OMe)-RNA/[All-RP-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription-Reference-Cited by-同舟云学术

LNA units present in the (2′-OMe)-RNA strand stabilize parallel duplexes (2′-OMe)-RNA/[All-RP-PS]-DNA and parallel triplexes (2′-OMe)-RNA/[All-RP-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription

Published:2015 Issue:8 Volume:13 Page:2375-2384
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Maciaszek Anna¹²³⁴⁵,Krakowiak Agnieszka¹²³⁴⁵,Janicka Magdalena¹²³⁴⁵,Tomaszewska-Antczak Agnieszka¹²³⁴⁵,Sobczak Milena¹²³⁴⁵,Mikołajczyk Barbara¹²³⁴⁵,Guga Piotr¹²³⁴⁵

Affiliation:

1. Centre of Molecular and Macromolecular Studies

2. Polish Academy of Sciences

3. Department of Bioorganic Chemistry

4. 90-363 Lodz

5. Poland

Abstract

LNA units stabilize (RNA/LNA)/R_P-PS-DNA/RNA triplexes and efficiently inhibit reverse transcription of target RNA.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry