Stereoselective access to 2-deoxy-2-trifluoromethyl sugar mimetics by trifluoromethyl-directed 1,2-<i>trans</i> glycosylation-Reference-Cited by-同舟云学术

Stereoselective access to 2-deoxy-2-trifluoromethyl sugar mimetics by trifluoromethyl-directed 1,2-trans glycosylation

Published:2023 Issue:10 Volume:10 Page:2405-2415
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Mestre Jordi¹^ORCID,Bascuas Isabel¹^ORCID,Bernús Miguel¹^ORCID,Castillón Sergio¹^ORCID,Boutureira Omar¹^ORCID

Affiliation:

1. Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/Marcel·lí Domingo 1, 43007 Tarragona, Spain

Abstract

A general methodology featuring a trifluoromethyl-directed 1,2-trans glycosylation reaction as a key step has been developed to give access to various 2-CF3-glycoconjugates, including carbohydrate epitopes, amino acids, and lipids.

Funder

Agencia Estatal de Investigación

Universitat Rovira i Virgili

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00274H

Reference121 articles.

1. Strategies for the Development of Glycomimetic Drug Candidates

2. Designing sugar mimetics: non-natural pyranosides as innovative chemical tools

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