Photoredox radical/polar crossover enables C–H <i>gem</i>-difunctionalization of 1,3-benzodioxoles for the synthesis of monofluorocyclohexenes-Reference-Cited by-同舟云学术

Photoredox radical/polar crossover enables C–H gem-difunctionalization of 1,3-benzodioxoles for the synthesis of monofluorocyclohexenes

Published:2023 Issue:22 Volume:14 Page:6045-6051
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Tian Jiabao¹,Zhou Lei¹^ORCID

Affiliation:

1. School of Chemistry, Sun Yat-Sen University, Panyu District, Guangzhou 510006, China

Abstract

A sequential C–H gem-difunctionalization of 1,3-benzodioxoles with α-trifluoromethyl alkenes and electron-deficient alkenes in a redox-neutral radical polar crossover manifold have been developed for the synthesis of monofluorocyclohexenes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC00912B

Reference65 articles.

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4. Recent Advances in Mono‐ and Difunctionalization of Unactivated Olefins

5. Recent Advances in Photoredox‐Mediated Radical Conjugate Addition Reactions: An Expanding Toolkit for the Giese Reaction

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