Base-Mediated Regioselective [3 + 3] Annulation of Alkylidene Malononitriles with Trifluoromethyl Alkenes via Dual C

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Base-Mediated Regioselective [3 + 3] Annulation of Alkylidene Malononitriles with Trifluoromethyl Alkenes via Dual C–F Bond Cleavage

Published:2024-08-26 Issue:35 Volume:26 Page:7452-7456
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Li Mingqiang¹,Zeng Weidi¹,Abdukader Ablimit¹^ORCID,Wu Shaofeng¹,Zhou Lei¹²^ORCID

Affiliation:

1. State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi 830046, Xinjiang, P. R. China

2. Institute of Green Chemistry and Molecular Engineering, School of Chemistry, SunYat-Sen University, Guangzhou, 510275, China

Funder

Natural Science Foundation of Xinjiang Uygur Autonomous Region

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.4c02788

Reference41 articles.

1. aWang, G.; Tang, W.; Bidigare, R. R. Natural Products; Springer, Berlin, 2005; pp 197–227.

2. Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery

3. Convergent Strategies in Total Syntheses of Complex Terpenoids

4. Fluorine in medicinal chemistry

5. The Unique Role of Fluorine in the Design of Active Ingredients for Modern Crop Protection

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