Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C

Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C–H bonds

Published:2018 Issue:71 Volume:54 Page:9985-9988
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Meanwell Michael¹²³⁴⁵,Lehmann Johannes¹²³⁴⁵,Eichenberger Marc⁶⁷⁸⁹¹⁰,Martin Rainer E.⁶⁷⁸⁹¹⁰^ORCID,Britton Robert¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Simon Fraser University

3. Burnaby

4. British Columbia

5. Canada

6. Medicinal Chemistry

7. Roche Pharma Research and Early Development (pRED)

8. Roche Innovation Center Basel

9. F. Hoffmann-La Roche Ltd

10. CH-4070 Basel

Abstract

Acyl fluorides are produced through the direct fluorination of aldehydic C–H bonds.

Funder

Natural Sciences and Engineering Research Council of Canada

Michael Smith Foundation for Health Research

F. Hoffmann-La Roche

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC06375C

Reference55 articles.

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2. The medicinal chemist's toolbox for late stage functionalization of drug-like molecules

3. Recent Advances in Radical C–H Activation/Radical Cross-Coupling

4. Monofluorination of Organic Compounds: 10 Years of Innovation

5. Fluorine in medicinal chemistry

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