A facile and metal-free domino reaction of TsDAM and 2-alkenylarylaldehyde: An easy access to 8-hydroxy-2,8-dihydro indeno [2,1-c]pyrazoles-Reference-Cited by-同舟云学术

A facile and metal-free domino reaction of TsDAM and 2-alkenylarylaldehyde: An easy access to 8-hydroxy-2,8-dihydro indeno [2,1-c]pyrazoles

Published:2021 Issue:18 Volume:19 Page:4118-4125
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ramu Gopathi¹²³⁴⁵,Kodiripaka Bheeshma Geetanjali¹²³⁴,Raga Chaitanya Kalakonda¹²³⁴⁵,Nagendra Babu Bathini¹²³⁴⁵^ORCID

Affiliation:

1. Department of Fluoro-AgroChemicals

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500 007

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

An efficient straightforward greener and metal free domino approach towards the synthesis of 8-hydroxy-2,8-dihydroindeno[2,1-c]pyrazoles via [3 + 2] cycloaddition of substituted alkenes and TosylDiAzoMethane (TsDAM).

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00262G

Reference38 articles.

1. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site

2. Methyl 3-((6-Methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)amino)benzoate (GN39482) as a Tubulin Polymerization Inhibitor Identified by MorphoBase and ChemProteoBase Profiling Methods

3. 3D-QSAR CoMFA study on indenopyrazole derivatives as cyclin dependent kinase 4 (CDK4) and cyclin dependent kinase 2 (CDK2) inhibitors

4. Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3

5. Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 2. Probing the Indeno Ring Substituent Pattern

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