Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site

Published:2016-05-20 Issue:11 Volume:59 Page:5341-5355
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Yan-Na¹,Wang Jing-Jing¹,Ji Ya-Ting¹,Zhao Guo-Dong¹,Tang Long-Qian¹,Zhang Cheng-Mei¹,Guo Xiu-Li¹,Liu Zhao-Peng¹

Affiliation:

1. Institute of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences and ‡Department of Pharmacology, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, P. R. China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00071

Reference57 articles.

1. Microtubule dynamics

2. Chromosome-Microtubule Interactions During Mitosis

3. Tubulins - The Target for Anticancer Therapy