Mechanochemical approaches towards the in situ confinement of 5-FU anti-cancer drug within MIL-100 (Fe) metal–organic framework
Author:
Affiliation:
1. Multifunctional Materials and Composites (MMC) Laboratory
2. Department of Engineering Science
3. University of Oxford
4. Oxford
5. UK
Abstract
Low-cost mechanochemistry methods for in situ confinement of “guest” drug molecules into a “host” metal–organic framework to yield nanoscale guest@host drug delivery systems.
Funder
Fundação de Amparo à Pesquisa do Estado de Minas Gerais
H2020 European Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/CE/D0CE00638F
Reference23 articles.
1. New synthetic routes towards MOF production at scale
2. Advances in Solid-State Transformations of Coordination Bonds: From the Ball Mill to the Aging Chamber
3. Guest–host interactions of nanoconfined anti-cancer drug in metal–organic framework exposed by terahertz dynamics
4. Amorphous metal–organic frameworks for drug delivery
5. Synthesis by extrusion: continuous, large-scale preparation of MOFs using little or no solvent
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