Synthesis of C4-alkynylisoxazoles via a Pd-catalyzed Sonogashira cross-coupling reaction-Reference-Cited by-同舟云学术

Synthesis of C4-alkynylisoxazoles via a Pd-catalyzed Sonogashira cross-coupling reaction

Published:2019 Issue:16 Volume:9 Page:8894-8904
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Yang Wen¹²³⁴⁵,Yao Yongqi¹²³⁴⁵,Yang Xin¹²³⁴⁵,Deng Yingying¹²³⁴⁵,Lin Qifu¹²³⁴⁵,Yang Dingqiao¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Theoretical Chemistry of Environment

2. Ministry of Education

3. School of Chemistry and Environment

4. South China Normal University

5. Guangzhou 510006

Abstract

A Pd-catalyzed Sonogashira cross-coupling reaction for the synthesis of C4-alkynylisoxazoles from 3,5-disubsitituted-4-iodoisoxazoles and terminal alkynes was described, which could afford the corresponding products with high yield (up to 98%).

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA00577C

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