Exploration of cytotoxic potential and tubulin polymerization inhibition activity of <i>cis</i>-stilbene-1,2,3-triazole congeners-Reference-Cited by-同舟云学术

Exploration of cytotoxic potential and tubulin polymerization inhibition activity of cis-stilbene-1,2,3-triazole congeners

Published:2023 Issue:3 Volume:14 Page:482-490
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Bora Darshana¹,Samir Khan Mehtab¹,Sharma Anamika²,Chilvery Shrilekha²,Bansod Sapana²,John Stephy Elza¹,Ali Khan Mursalim¹,Godugu Chandraiah²,Shankaraiah Nagula¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad – 500 037, India

2. Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad – 500 037, India

Abstract

To scrutinize cis-stilbene based molecules with potential anticancer and tubulin polymerization inhibition activity, a new series of cis-stilbene-1,2,3-triazole congeners was designed and synthesized via a click chemistry protocol.

Funder

Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D2MD00400C

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