The catalyst-free decarboxylative dearomatization of isoquinolines with β-keto acids and sulfonyl chlorides in water: access to dihydroisoquinoline derivatives-Reference-Cited by-同舟云学术

The catalyst-free decarboxylative dearomatization of isoquinolines with β-keto acids and sulfonyl chlorides in water: access to dihydroisoquinoline derivatives

Published:2020 Issue:42 Volume:18 Page:8646-8652
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Yutong¹²³⁴,Han Fuzhong¹²³⁴⁵,Jia Lina¹²³⁴⁵^ORCID,Hu Xiangping⁶⁷⁸⁴^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering

2. Qiqihar University

3. Qiqihar 161006

4. China

5. Heilongjiang Provincial Key Laboratory of Catalytic Synthesis for Fine Chemicals

6. Dalian Institute of Chemical Physics

7. Chinese Academy of Sciences

8. Dalian 116023

Abstract

An efficient and concise catalyst-free one-pot synthetic protocol for obtaining dihydroisoquinoline derivatives has been developed via the three-component condensation of isoquinolines with β-keto acids and sulfonyl chlorides.

Funder

Heilongjiang Youth Development Foundation

University Nursing Program for Young Scholar with Creative Talents in Heilongjiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01799J

Reference58 articles.

1. Multicomponent domino reactions for the synthesis of biologically active natural products and drugs