FeCl3-catalyzed oxidative decarboxylation of aryl/heteroaryl acetic acids: preparation of selected API impurities-Reference-Cited by-同舟云学术

FeCl3-catalyzed oxidative decarboxylation of aryl/heteroaryl acetic acids: preparation of selected API impurities

Published:2020 Issue:41 Volume:18 Page:8459-8466
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gangadurai Chinnakuzhanthai¹²³⁴^ORCID,Illa Giri Teja¹²³⁴,Reddy D. Srinivasa¹²³⁴⁵^ORCID

Affiliation:

1. Organic Chemistry Division

2. CSIR-National Chemical Laboratory

3. Pune-411008

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

An iron catalyzed one-pot, environmentally benign protocol for the oxidative decarboxylation of aryl/heteroaryl acetic acids to synthesize corresponding carbonyl compounds and five important API impurities is described.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01790F

Reference44 articles.

1. Impurity profile: Significance in Active Pharmaceutical Ingredient

2. A Review on Significances of Impurity Profiling

3. Large-Scale Oxidations in the Pharmaceutical Industry

4. Photoredox-Catalyzed Decarboxylative Oxidation of Arylacetic Acids

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