Sequential aza-Piancatelli rearrangement/Friedel–Crafts alkylation for the synthesis of pyrrolo[1,2-d]benzodiazepine derivatives-Reference-Cited by-同舟云学术

Sequential aza-Piancatelli rearrangement/Friedel–Crafts alkylation for the synthesis of pyrrolo[1,2-d]benzodiazepine derivatives

Published:2016 Issue:3 Volume:14 Page:1111-1116
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Subba Reddy B. V.¹²³⁴,Vikram Reddy Y.¹²³⁴,Singarapu Kiran Kumar⁵²³⁴

Affiliation:

1. Natural Product Chemistry

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad – 500 007

4. India

5. Centre for Nuclear Magnetic Resonance

Abstract

2-Furylcarbinols undergo a smooth aza-Piancatelli rearrangement followed by Friedel–Crafts alkylation with (1H-pyrrol-1-yl)aniline, in the presence of In(OTf)₃ at room temperature to afford the corresponding hexahydrobenzo[b]cyclopenta[f]pyrrolo[1,2-d][1,4]diazepin-11(4aH)-one scaffolds.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB01616A

Reference35 articles.

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