Affiliation:
1. Department of Organic Synthesis and Process Chemistry CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India
2. Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India
3. Centre for X-ray Crystallography Department of Analytical & Structural Chemistry CSIR-Indian Institute of Chemical Technology Hyderabad 500007 India
Abstract
AbstractCascade aza‐Piancatelli reaction and [3+3]/[4+2] cycloaddition reactions are carried out using the ideality principles of pot, atom, and step economy (PASE) synthesis. The reaction resulted in generation of octahydro‐4H‐cyclopenta[b]pyridin‐6‐one scaffolds. Moreover, octahydro‐5,7a‐epoxycyclopenta[cd]isoindol‐4‐one frameworks of gracilamine alkaloid and a novel decahydro‐1H‐dicyclopenta[cd,hi]isoindol‐6‐one were also realized in good yields with excellent regio‐ and diastereo‐selectivities.
Subject
General Chemistry,Catalysis,Organic Chemistry