Enzyme-free amplified detection of miRNA based on target-catalyzed hairpin assembly and DNA-stabilized fluorescent silver nanoclusters

Author:

Gu Jinqing12345,Qiao Zhenzhen12345,He Xiaoxiao12345,Yu Yanru12345,Lei Yanli12345ORCID,Tang Jinlu12345,Shi Hui12345ORCID,He Dinggeng678910,Wang Kemin12345ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics

2. College of Chemistry and Chemical Engineering

3. College of Biology

4. Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province

5. Hunan University

6. State Key Laboratory of Developmental Biology of Freshwater Fish

7. College of Life Sciences

8. Hunan Normal University

9. Changsha 410081

10. China

Abstract

A simple, cost-effective, sensitive, and selective strategy was developed for microRNA analysis using target-catalyzed hairpin assembly and fluorescent silver nanoclusters.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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