Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells

Author:

Wu Yanan12345,Meng Hong-Min12345,Chen Juan12345,Jiang Kemei12345,Yang Ran12345,Li Yingying12345,Zhang Ke6789,Qu Lingbo12345,Zhang Xiao-Bing1011125ORCID,Li Zhaohui12345ORCID

Affiliation:

1. Institute of Chemical Biology and Clinical Application at the First Affiliated Hospital

2. Henan Joint International Research Laboratory of Green Construction of Functional Molecules and Their Bioanalytical Applications

3. College of Chemistry, Zhengzhou University

4. Zhengzhou 450001

5. P. R. China

6. Department of Chemistry and Chemical Biology

7. Northeastern University

8. Boston

9. USA

10. College of Chemistry and Chemical Engineering

11. Hunan University

12. Changsha 410082

Abstract

An accelerated DNAzyme-based fluorescent nanoprobe was developed for rapid and highly sensitive detection of microRNA in live cells.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Key Scientific Research Project of Colleges and Universities in Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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