13C stable isotope labeling followed by ultra-high performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (UHPLC/Q-TOF MS) was applied to identify the metabolites of honokiol in rat small intestines-Reference-Cited by-同舟云学术

13C stable isotope labeling followed by ultra-high performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (UHPLC/Q-TOF MS) was applied to identify the metabolites of honokiol in rat small intestines

Published:2015 Issue:6 Volume:7 Page:2488-2496
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Ye Na¹²³⁴⁵,Tang Minghai⁶⁷⁸⁹¹⁰,Ye Haoyu⁶⁷⁸⁹¹⁰,Wang Chunyan¹²³⁴⁵,Wang Chunyu⁶⁷⁸⁹¹⁰,Yang Qiunan¹²³⁴⁵,Wan Li¹²³⁴⁵,Chen Lijuan⁶⁷⁸⁹¹⁰

Affiliation:

1. School of Pharmacy

2. Chengdu University of TCM

3. The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine

4. State Key Laboratory Breeding Base of Systematic Research

5. Development and Utilization of Chinese Medicine Resources

6. State Key Laboratory of Biotherapy

7. West China Hospital

8. West China Medical School

9. Sichuan University

10. Chengdu 610041

Abstract

Honokiol, as a pharmacological active small-molecule, has received significant attention for its strong pharmacological effects without remarkable toxicity.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/AY/C4AY02403F

Reference37 articles.

1. In vitro growth inhibition of human cancer cells by novel honokiol analogs

2. Behavioural Pharmacological Characteristics of Honokiol, an Anxiolytic Agent Present in Extracts of Magnolia Bark, Evaluated by an Elevated Plus-maze Test in Mice

3. Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells

4. Antidiabetic and Anti-oxidative Effects of Honokiol on Diabetic Rats Induced by High-fat Diet and Streptozotocin

5. Combined administration of the mixture of honokiol and magnolol and ginger oil evokes antidepressant-like synergism in rats

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