Recent advances in iron-complexes as drug candidates for cancer therapy: reactivity, mechanism of action and metabolites
Author:
Affiliation:
1. Université de Lorraine
2. CNRS
3. L2CM UMR 7053
4. F-54000 Nancy
5. France
6. LPCT UMR 7019
7. CRAN UMR 7039
Abstract
In this perspective, we discuss iron-complexes as drug candidates, and emphasize breakthroughs in the comprehension of their structure–activity relationship, metabolization pathways, sub-cellular localization and influence on iron homeostasis.
Funder
Université de Lorraine
Centre National de la Recherche Scientifique
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02135K
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