Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitors-Reference-Cited by-同舟云学术

Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitors

Published:2015 Issue:12 Volume:6 Page:2163-2169
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Steinkamp Anne-Dorothee¹²³⁴,Seling Nico¹²³⁴,Lee Soojung⁵⁶⁷⁸,Boedtkjer Ebbe⁵⁶⁷⁸,Bolm Carsten¹²³⁴

Affiliation:

1. Institute of Organic Chemistry

2. RWTH Aachen University

3. 52056 Aachen

4. Germany

5. Department of Biomedicine

6. Aarhus University

7. DK-8000 Aarhus C

8. Denmark

Abstract

Two analogs of S0859 have been synthesized and their effects on Na⁺,HCO₃⁻ co-transport activity have been evaluated.

Funder

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00367A

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