Synthesis of C-functionalized TE1PA and comparison with its analogues. An example of bioconjugation on 9E7.4 mAb for multiple myeloma 64Cu-PET imaging-Reference-Cited by-同舟云学术

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Synthesis of C-functionalized TE1PA and comparison with its analogues. An example of bioconjugation on 9E7.4 mAb for multiple myeloma 64Cu-PET imaging

Published:2018 Issue:23 Volume:16 Page:4261-4271
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Le Bihan Thomas¹²³⁴⁵^ORCID,Navarro Anne-Sophie⁶⁷⁸⁹⁵,Le Bris Nathalie¹²³⁴⁵^ORCID,Le Saëc Patricia⁶⁷⁸⁹⁵,Gouard Sébastien⁶⁷⁸⁹⁵,Haddad Ferid¹⁰¹¹⁵^ORCID,Gestin Jean-François⁶⁷⁸⁹⁵,Chérel Michel⁶⁷⁸⁹⁵,Faivre-Chauvet Alain⁶⁷⁸⁹⁵,Tripier Raphaël¹²³⁴⁵^ORCID

Affiliation:

1. Université de Brest

2. UMR-CNRS 6521/IBSAM

3. UFR Sciences et Techniques

4. 29238 Brest

5. France

6. Université de Nantes

7. Centre de Recherche en Cancérologie et Immunologie Nantes Angers (CRCINA)

8. Unité INSERM 1232 – CNRS 6299

9. 44007 Nantes Cedex

10. Groupement d'Intérêt Public ARRONAX

11. 44800 Saint-Herblain

Abstract

Functionalisation of a TE1PA ligand to make it bifunctional, while maintaining its chelating properties.

Funder

Centre National de la Recherche Scientifique

Ligue Contre le Cancer

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00499D

Reference50 articles.

1. Molecular Imaging of Cancer with Copper-64 Radiopharmaceuticals and Positron Emission Tomography (PET)

2. New Technologies for Human Cancer Imaging

3. Brain PET in the Diagnosis of Alzheimer’s Disease

4. PET Imaging of Atherosclerotic Disease: Advancing Plaque Assessment from Anatomy to Pathophysiology

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