Highly sensitive detection of C-reactive protein using a novel dissolution approach in a dye-doped silica nanoparticle-based fluorescence immunoassay

Author:

Nooney Robert1234ORCID,Rebello Valerie1234,Keegan Gemma1234,O'Connell Claire L.5234,Byrne Daragh5234,McDonagh Colette5234

Affiliation:

1. Biomedical Diagnostics Institute

2. Dublin City University

3. Dublin 9

4. Ireland

5. School of Physical Sciences

Abstract

A novel dissolution approach was used to achieve enhanced sensitivity in a nanoparticle (NP) immunoassay for the detection of a cardiovascular disease marker, C-reactive protein (CRP).

Funder

Irish Research Council

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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