Polyisobutylene-based glycopolymers as potent inhibitors for <i>in vitro</i> insulin aggregation-Reference-Cited by-同舟云学术

Polyisobutylene-based glycopolymers as potent inhibitors for in vitro insulin aggregation

Published:2022 Issue:45 Volume:10 Page:9446-9456
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Dey Asmita¹,Haldar Ujjal²,Rajasekhar Tota²^ORCID,Ghosh Pooja¹,Faust Rudolf²,De Priyadarsi¹^ORCID

Affiliation:

1. Polymer Research Centre and Centre for Advanced Functional Materials, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur – 741246, Nadia, West Bengal, India

2. Polymer Science Program, Department of Chemistry, University of Massachusetts Lowell, One University Avenue, Lowell, Massachusetts 01854, USA

Abstract

In this manuscript, we have synthesized a family of water-soluble PIB-based glycopolymers and observed their efficiency in inhibition of insulin fibrillation.

Funder

Science and Engineering Research Board

Indian Institute of Science Education and Research Kolkata

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2022/TB/D2TB01856J

Reference57 articles.

1. Protein misfolding, aggregation and mechanism of amyloid cytotoxicity: An overview and therapeutic strategies to inhibit aggregation

2. Oligomeric procyanidins inhibit insulin fibrillation by forming unstructured and off-pathway aggregates